Hu CLEC7A (Dectin-1) PE 15E2 100Tst
货号：
564471 基本售价：
9765.0 元 规格：
100Tst
产品信息
概述| 货号 | 564471 |
| 描述 | The 15E2 monoclonal antibody specifically binds to CLEC7A (C-type lectin domain family 7 member A) which is also known as Dectin-1 (Dendritic cell-associated C-type lectin 1), and BGR (Beta-glucan receptor). CLEC7A is a type II transmembrane C-type lectin that contains a C-terminal stalk with a carbohydrate recognition domain (CRD) in the extracellular domain, a transmembrane segment, and an ITAM containing cytoplasmic tail. This protein is highly expressed on dendritic cells. It is also expressed on B cells, monocytes, eosinophils, mast cells, macrophages, endothelial cells, and is lowly expressed on some subsets of T cells. CLEC7A binds to beta-glucan polymers and functions as a pattern recognition receptor in innate immune response to fungal and bacterial pathogens. The 15E2 antibody can reportedly stimulate dendritic cells to costimulate immune responses. |
| 别名 | CLEC7A; CLC7A; BGR; CLECSF12; CANDF4 |
| 同种亚型 | Mouse BALB/c IgG2a, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Dectin-1 Recombinant Protein |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
