Hu CD137 Pure H41BB-M127 500ug
货号：
552532 基本售价：
9570.0 元 规格：
500ug
产品信息
概述| 货号 | 552532 |
| 描述 | Human 4-1BB, also known as CDw137, is a type I transmembrane glycoprotein belonging to the tumor necrosis factor receptor (TNFR) superfamily. Naοve T cells lack the 4-1BB, which is not only induced upon T cell activation, but also remains on activated T cells. It has been reported that the expression of 4-1BB is restricted to primed CD4+ and CD8+ cells. When triggered by either 4-1BB ligand or antibody ligation, the 4-1BB molecule can act as a co-stimulator to induce T-cell activation and proliferation. In recent studies, 4-1BB has been emphasized for its effect on the development and survival of functionally active effector CD8 (+) T cells against tumors, virus infections, allogenic immune responses, and for potential therapeutic application. |
| 别名 | 4-1BB, CDw137 |
| 同种亚型 | IgG1,κ |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | ELISA Cap. |
性能| 供应商 | BD Pharmingen |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
