BV421 Mouse Anti-Human TRAIL-R2 (CD262)
货号：
743835 基本售价：
9000.0 元 规格：
EA
产品信息
概述| 货号 | 743835 |
| 描述 | The YM366 monoclonal antibody specifically binds to TNF-related apoptosis-inducing ligand receptor 2 (TRAIL Receptor 2, TRAIL-R2) which is also known as, CD262, Death receptor 5 (DR5), TRICK2, or KILLER. CD262 is a type I transmembrane protein that is encoded by TNFRSF10B (Tumor necrosis factor receptor superfamily, member 10b). CD262 forms a homotrimeric receptor complex that can bind homotrimeric TRAIL (CD253/APO-2 Ligand) and transduce apoptotic signals intracellularly through its cytoplasmic death domain (DD). CD262 is differentially expressed on cells from a wide variety of normal tissues and tumors. CD262 expression is upregulated by I nterferon-α(IFN-α). |
| 别名 | TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9 |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human DR5/TRAIL-R2 Recombinant Protein |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV421 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
