BV421 Mouse Anti-Human CD125
货号:
743927 基本售价:
9000.0 元 规格:
EA
产品信息
概述货号 | 743927 |
描述 | The A14 monoclonal antibody specifically recognizes the α chain of the Interleukin-5 R eceptor (IL-5Rα) , which is also known as CD125. IL- 5Rα is a 55-60 kDa type I transmembrane glycoprotein that is expressed on B1 B cells, eosinophils, basophils and mast cells. The IL-5Rα chain associates with CD131 (Common β-chain) which serves as the signaling c ommon β-chain subunit of the IL-5R complex as well as for the Interleukin-3 (IL-3R) and GM-CSF receptor (GM-CSFR) complexes. IL-5 promotes the growth and differentiation of eosinophil precursors and activates mature eosinophils. Clone A14 was developed using IL-5R α-transfected cells as immunogen. This antibody binding can be bloc ked by IL-5. |
别名 | CD125; IL-5Rα; IL5RA; IL5R |
同种亚型 | Mouse IgG1, κ |
反应种属 | Human (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | IL-5Rα-transfected cells |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV421 under optimal conditions that minimize unconjugated dye and antibody.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |