BV650 Mouse Anti-Human Invariant NK T Cell
货号：
744000 基本售价：
9000.0 元 规格：
EA
产品信息
概述| 货号 | 744000 |
| 描述 | Monoclonal antibody 6B11 reacts with a unique determinant in the CDR3 region of the invariant (V α24-Jα Q) TCR chain. Thus 6B11 identifies a subset of all V α 24 positive T cells. The binding of the PE-conjugate of 6B11 can be partially blocked by other antibodies specific for V α 24 (BD Biosciences Pharmingen, data not shown). This invariant chain is expressed on invariant NK T cells, which are a small subset of T lymphocytes that also express other NK cell molecules such as CD161. Invariant NK T cells have been reported to play an immunoregulatory role. The V α24-Jα Q interacts with the CD1d protein. Invariant NK T cells can be specifically activated by CD1d-presented antigen resulting in rapid production of IL-4 and IFN (also known as IFN- γ ). Studies of NK T cells describe their role in anti-tumor immunity and autoimmunity. |
| 别名 | Vα24JαQ TCR Chain |
| 同种亚型 | Mouse C57BL/6 IgG1, κ |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Peptide from CDR3 loop of the invariant TCR V24 sequence |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
