BV786 Mouse Anti-Human Disialoganglioside GD2
货号：
744073 基本售价：
9000.0 元 规格：
EA
产品信息
概述| 货号 | 744073 |
| 描述 | Gangliosides are sialic-acid bearing glycolipids that are expressed on the surface of all mammalian cells, and are likely involved in mediating cell-substratum interactions. They are important target antigens for antibody dependent cellular cytotoxicity (ADCC) of human melanoma and neuroblastoma cells. Human melanoma cells produce gangliosides, designated as GD2 and GD3 which are deposited in the subtratum-attached material, and may play a significant role in the melanoma metastatic phenotype. Clone 14.G2a specifically reacts with human and mouse GD2 ganglioside. LAN-1 human neuroblastoma cells were used as immunogen. Clone 14.G2a is an isotype switch variant selected from the parental IgG3-producing hybridoma 14.18 and has identical reactivity as the parental antibody. Clone 14.G2a is routinely tested by flow cytometry using M21 human melanoma cells. |
| 别名 | GD2; Disialoganglioside GD2; Ganglioside GD2 |
| 同种亚型 | Mouse BALB/c IgG2a |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | LAN-1 human neuroblastoma cells |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV786 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
