BV650 Mouse Anti-Human CD51/CD61
货号:
744091 基本售价:
9000.0 元 规格:
EA
产品信息
概述货号 | 744091 |
描述 | The 23C6 monoclonal antibody specifically binds to the Integrin αvβ3 heterodimeric complex (CD51/CD61) that is expressed on osteoclasts, endothelial cells, macrophages, melanoma cells, some B cells and in very low amounts on platelets. This antibody has be en reported to crossreact with chicken and rabbit, but not with rat αvβ3. The integrin αvβ3 heterodimer, often referred to as the vitronectin receptor, binds several ligands in addition to vitronectin including, von Willebrand factor, thrombospondin, osteopontin, bone sialoprotein, neural adhesion molecule L1, laminin, fibronectin, and fibrinogen. The binding of some ligands to the vitronectin receptor has been reported to be inhibited by the 23C6 monoclonal antibody. |
别名 | Vitronectin Receptor; Itgav/Itgb3; Integrins alpha V, beta 3 |
同种亚型 | Mouse BALB/c IgG1, κ |
反应种属 | Human (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | Human Osteoclastomas |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |