BUV395 Mouse Anti-Human CD220
货号：
744433 基本售价：
9000.0 元 规格：
EA
产品信息
概述| 货号 | 744433 |
| 描述 | The 3B6 monoclonal antibody specifically recognizes the Insulin Receptor (IR), a glycoprotein composed of two extracellular α -subunits (130 kDa) and two transmembrane β -subunits (95 kDa). It is expressed on human hematopoietic and non-hematopoietic cells, but unlike the insulin-like growth factor receptor (IGF-IR), which is ubiquitous, the insulin receptor is restricted to major target tissues of insulin action. Upon binding insulin, the IR subunits form a heterotetramer of two α and two β subunits resulting in autophosphorylation and activation of the tyrosine kinase activity of the receptor. This ligand-receptor interaction is important in regulating cell metabolism and growth. 3B6/IR monoclonal antibody reacts similarly to anti-human IR α , clone 47-9, an α -subunit antibody. |
| 别名 | Insulin Receptor; Insulin R; IR; INSR; HHF5 |
| 同种亚型 | Mouse IgG1, κ |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BUV395 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
