BV786 Mouse Anti-Human CD132
货号：
742574 基本售价：
9000.0 元 规格：
EA
产品信息
概述| 货号 | 742574 |
| 描述 | The AG184 monoclonal antibody specifically binds to the 65-70 kDa common γ subunit ( γ c) that is shared by the IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21 receptor complexes. The γ c receptor is a type 1 transmembrane glycoprotein that is constitutively expressed by most peripheral T and B lymphocytes, NK cells, monocytes and granulocytes. The cytoplasmic domain of the γ c chain plays an important role in cytokine-mediated signal transduction. By immunofluorescent staining and flow cytometric analyses, the AG184 antibody has been shown to specifically recognize human γ c expressed by cell lines including human γ c gene-transfected cell lines which are known to express the human γ c chain. The AG184 antibody can bind the γ c chain in the receptors complexed with IL-2, IL-4, or IL-7, indicating that the antibody recognizes an epitope which is distinct from the cytokine binding site of the γ c chain. |
| 别名 | IL2RG; IL-2RG; IL-2Rγ; Common gamma chain; γc; CIDX; SCIDX; SCIDX1; IMD4 |
| 同种亚型 | Mouse IgG1, κ |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV786 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
