BV786 Mouse Anti-Human CD39
货号：
742523 基本售价：
9000.0 元 规格：
EA
产品信息
概述| 货号 | 742523 |
| 描述 | The TU66 monoclonal antibody reacts with human CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), an ectoenzyme that degrades ATP to AMP. It is a member of the ectonucleoside triphosphate dihydrolases (E-NTPDases) family involved in the regulation of extracellular nucleotide catabolism by controlling the extracellular nucleoside triphosphate pool (NTP). CD39 is expressed on a subset of T cells, B cells and dendritic cells, with weak staining of monocytes and granulocytes. Recently, CD39 has been found to be expressed primarily by immune-suppressive Foxp3(+) regulatory T (Treg) cells in both human and mice. In humans, CD39 is restricted to a subset of Foxp3+ regulatory effector/memory-like T cells. In mice, the enzyme is present on most, if not all, CD4+CD25+ cells. CD39 expression is driven by Foxp3 and it is thought that CD39 allows Treg cells to enter inflamed areas where high levels of ATP are present. |
| 别名 | ENTPD1; NTPDase-1; Ecto-ATPase 1; Ecto-ATPDase 1 |
| 同种亚型 | Mouse IgG2b, κ |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV786 under optimal conditions that minimize unconjugated dye and antibody.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
