BV510 Mouse Anti-Human CD4 v4
货号：
742651 基本售价：
9000.0 元 规格：
EA
产品信息
概述| 货号 | 742651 |
| 描述 | The L120 monoclonal antibody specifically recognizes CD4. CD4 is an ~59 kDa type I transmembrane glycoprotein that belongs to the Ig gene superfamily. CD4 is expressed on helper-inducer subset of T lymphocytes and monocytes. The CD4 antigen is involved in the Major Histocompatibility Complex (MHC) class II-restricted recognition of foreign antigens and has been identified as a receptor for HIV. The L120 antibody recognizes amino acids 306-370 of the antigen and does not block the binding of the gp120 of HIV, but inhibits the proliferation of CD4 T lymphocytes to MHC class II antigens. The CD4 antigen is present on most thymocytes, approximately 40% of peripheral blood lymphocytes, and at lower density on monocytes. Peripheral blood CD4+ T lymphocytes are lost over time during HIV infection, and this loss is correlated with disease progression. |
| 别名 | L3T4; T-cell surface antigen T4/Leu-3; W3/25; CD4 antigen (p55) |
| 同种亚型 | Mouse BALB/c IgG1 |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Peripheral Blood Lymphocytes |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV510 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
