BV786 Mouse Anti-Human P-glycoprotein
货号：
742852 基本售价：
9000.0 元 规格：
EA
产品信息
概述| 货号 | 742852 |
| 描述 | The 17F9 monoclonal antibody specifically binds to the 170-180 kDa transmembrane glycoprotein (P-glycoprotein), a product of the multidrug resistance-1 (MDR1) gene. This glycoprotein is expressed on MDR positive cells and has been reported to be expressed on many normal tissues, such as adrenal glands and endothelium, in the brain and skin. P-glycoprotein is known to impart drug resistance to cells by pumping many anti-cancer drugs out of the cytoplasm. 17F9 antibody is able to partially block the binding of UIC2 antibody (another MDR-specific monoclonal antibody). |
| 别名 | CD243; ABCB1; ABC20; CLCS; GP170; MDR1; P-GP; PGY1 |
| 同种亚型 | Mouse BALB/c IgG2b, κ |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human MDR1 Transfected Cell Line |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV786 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
