HU CD41A BV421 HIP8 50UG
货号:
740074 基本售价:
9000.0 元 规格:
50ug
产品信息
概述货号 | 740074 |
描述 | The HIP8 monoclonal antibody specifically binds to the α -chain of CD41. CD41 is also known as Integrin α IIb or Platelet GPIIb. The calcium-dependent complex of CD41 and CD61 ( β 3 integrin or GPIIIa) is normally expressed on platelets and megakaryocytes. The CD41/CD61 complex is the receptor for fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. CD41 (clone HIP8) completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. This antibody is useful in the morphological and physiological studies of platelets and megakaryocytes. |
别名 | ITGA2B; Integrin alpha-2b (αIIb); Platelet glycoprotein IIb (GPIIb) |
同种亚型 | Mouse BALB/c IgG1, κ |
反应种属 | Human (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | Purified platelet membrane glycoproteins |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV421 under optimal conditions that minimize unconjugated dye and antibody.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |