Hu CD212 BB515 2.4E6 100Tst
货号：
565043 基本售价：
8880.0 元 规格：
100Tst
产品信息
概述| 货号 | 565043 |
| 描述 | The 2.4E6 monoclonal antibody specifically binds to CD212, which is also known as the Interleukin-12 Receptor beta-1 chain (IL12RB1/IL-12RB1/ IL-12Rβ1 ). CD212 serves as a subunit for the functional IL-12 Receptor (IL-12R β1-IL-12Rβ 2) and IL-23 Receptor (IL-12R β 1-IL-23R) complexes. CD212 is expressed on T cells, B cells, or NK cells. CD212 is a type I transmembrane glycoprotein that belongs to the hemopoietin receptor superfamily. CD212 is responsible for binding to the IL-12 p40 subunit that is common to the heterodimeric IL-12 and IL-23 cytokines. IL-12 and IL-23 are immunomodulatory cytokines produced mainly by antigen-presenting cells (APC) including monocytes and dendritic cells. These cytokines have overlapping as well as distinct biological activities. |
| 别名 | IL-12R beta 1, IL-12 receptor β1 subunit |
| 同种亚型 | Mouse IgG1, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | PHA-activated Human PBMC |
| 标记 | BB515 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BB515 under optimum conditions and unconjugated antibody was removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
