Hu CD167a Alexa 647 48B3 50ug
货号：
566236 基本售价：
8415.0 元 规格：
50ug
产品信息
概述| 货号 | 566236 |
| 描述 | The 48B3 monoclonal antibody specifically binds to CD167a which is also known as Discoidin domain receptor tyrosine kinase 1 (DDR1), Cell adhesion kinase (CAK), Mammary carcinoma kinase 10 (MCK10), or Neuroepithelial tyrosine kinase. CD167a is expressed on epithelial cells and at relatively low levels on immature dendritic cells and B lymphocytes. CD167a is a single-pass type I transmembrane glycoprotein. The extracellular CD167a discoidin homology domain mediates binding to various types of collagen. The binding of collagen leads to the activation of the cytoplasmic tyrosine kinase domain. The CD167a receptor tyrosine kinase (RTK) plays a role in regulating cellular proliferation, morphogenesis, differentiation, and collagen synthesis, as well as the synthesis of metalloproteases and extracellular matrix remodeling. CD167a may be involved in tumor invasion and metastasis. The 48B3 antibody does not recognize CD167b (DDR2). |
| 别名 | CD167; CAK; DDR; EDDR1; HGK2; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE |
| 同种亚型 | Mouse BALB/c IgM, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human DDR1 Transfected Cell Line |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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| 存储溶液 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
