Hu CD62E PE-Cy5 68-5H11 100Tst
货号：
550040 基本售价：
8060.0 元 规格：
100Tst
产品信息
概述| 货号 | 550040 |
| 描述 | The 68-5H11 monoclonal antibody specifically binds to CD62E. This adhesion molecule is a 97-115 kDa type I transmembrane glycoprotein that is encoded by the SELEgene. CD62E is also known as E-selectin, Endothelial-leukocyte adhesion molecule-1 (ELAM-1), and Leukocyte endothelial cell adhesion molecule 2 (LECAM-2). CD62E is minimally expressed by unstimulated endothelium. Activated endothelial cells upregulate surface CD62E expression in response to various activators including inflammatory cytokines such as Interleukin-1 and Tumor Necrosis Factor. CD62E plays a role in leucocyte extravasation by promoting leucocyte rolling on activated endothelial cells during inflammation. CD62E may also play a role in the metastasis of certain tumor cells. The adhesion between endothelial CD62E molecules and a carbohydrate ligand on neutrophils is inhibited by the mAb 68-5H11. |
| 别名 | SELE; E-selectin; Selectin E; ELAM; ELAM1; ESEL; LECAM2 |
| 同种亚型 | IgG1,κ |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 标记 | PE-Cy5 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with PE-Cy5 (formerly known as BD Cy-Chrome™) under optimum conditions, and unconjugated antibody and free PE-Cy5 were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
