BV711 Mouse Anti-Integrin αvβ5
货号：
743673 基本售价：
7000.0 元 规格：
EA
产品信息
概述| 货号 | 743673 |
| 描述 | The ALULA monoclonal antibody specifically binds to Integrin alpha v beta 5 ( αvβ5 ), which is also known as CD51/β5. Integrin αvβ5 is widely expressed by fibroblasts, endothelial cells, and vascular smooth muscle cells. It is involved in activation-dependent cell migration and cell adhesion to t he extracellular matrix. Integrin αvβ5 play s a major role in growth factor-induced angiogenesis in response to VEGF and TGF. The αv Integrins, αvβ5 andαvβ3, αre involved in tumor growth and are being targeted in cancer therapies. The ALULA clone specifically recognizes α v β5 integrin and functionally block s the interactio n between α v β5 and vitronectin. Although raised against mouse αvβ5 , the ALULA antibody crossreacts with human αvβ5. |
| 别名 | Integrin alpha v beta 5; αVβ5; CD51/β5 |
| 同种亚型 | Mouse 129, also known as 129/J or 129/SvJ IgG |
| 反应种属 | Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse fibroblasts expressing αvβ5 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV711 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
