Hu CD77 BV510 5B5 100Tst
货号：
563630 基本售价：
6750.0 元 规格：
100Tst
产品信息
概述| 货号 | 563630 |
| 描述 | The 5B5 monoclonal antibody specifically binds to human CD77, a small neutral glycosphingolipid also referred to as globotriaosylceramide (Gb3), Burkitt s lymphoma associated antigen (BLA), ceramide trihexoside (CTH), and Pk blood group antigen. CD77 is expressed on a subset of germinal center B-lymphocytes including centroblasts that are found with greater frequency in tonsil and mucosal lymphoid tissues and less frequently in peripheral blood, bone marrow and spleen. It has been described as a receptor for Shiga Toxin, produced by Shigella dysenteriae, and Verotoxin 1 (VT1), produced by some strains of E. coli. CD19 has been reported as a ligand for CD77. This interaction may function in adhesion and signal transduction at a specific stage of B cell differentiation. Studies have shown that cross-linking CD77 induces apoptosis in some B cell lines. |
| 别名 | BLA; Gb3; Pk blood group antigen; CTH |
| 同种亚型 | Mouse BALB/c IgM, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Initially Adherent Human Peripheral Blood Cells |
| 标记 | BV51 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV510 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV510 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
