Hu CD3Epsilon APC APA1/1 100Tst
货号：
558257 基本售价：
6460.0 元 规格：
100Tst
产品信息
概述| 货号 | 558257 |
| 描述 | Monoclonal antibody APA1/1 reacts with the intracellular domain of the epsilon chain of the CD3 molecule (CD3-ε). This antibody does not react with the extracellular region of CD3-ε. The assembly of the T cell antigen receptor (TCR)-CD3 complex has been suggested to take place by pairwise interactions of the CD3-ε subunit with either CD3-γ or CD3-δ. These dimers then associate with the TCR heterodimer a/βorγ/δ, and the CD3-ζ homodimer to form the full complex. Studies show that antibodies APA1/1 and SP34 gave a strong reaction with COS cells singly transfected with CD3-ε. Other anti-CD3 antibodies (OKT3, WT31, UCHT1, Leu4) did not react with COS cells singly transfected with CD3-ε. This reagent could be useful for the study of T cell development or the study of conformational changes of CD3-ε upon ligand binding to TCR-CD3 complex. |
| 同种亚型 | IgG1,κ |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | IC/FC |
性能| 供应商 | BD Pharmingen |
| 标记 | APC |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
|
| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
