Hu PAK4 W/Cont Pure E40-883 50ug
货号：
551358 基本售价：
6003.0 元 规格：
50ug
产品信息
概述| 货号 | 551358 |
| 描述 | p21/Rac/Cdc42 activated kinases (PAKs) are serine/threonine kinases which regulate morphological and cytoskeletal changes in a variety of cell types, and are also implicated in MAP kinase pathways. PAKs contain an N-terminal regulatory domain and a C-terminal catalytic domain, and become activated following proteolytic cleavage between these regions. The activity of PAKs has been shown to be regulated by the GTPases Rac and Cdc42.1 Several members of the PAK family have been identified and implicated in regulation of the cytoskeletal organization induced by Rac and Cdc42, however, the cytoskeletal organizational change can occur independently of the known PAKs. PAK4 has been shown to provide a direct link between Cdc42 activation and cytoskeleton organization. PAK4 consists of 591 amino acids with a predicted molecular weight of about 64 kDa. The antibody recognizes human PAK4. A purified recombinant 6xHis-tagged fusion protein corresponding to the full length of human PAK4 was used as the immunogen. |
| 同种亚型 | IgG1 |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human PAK4 recombinant fusion protein |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Store the antibody Cat. No. 51-8102KC at 4°C. Store the HeLa control lysate Cat. No. 51-16516N at -20°C. |
