Hu HVEM (CD270) BV421 CW10 50Tst
货号:
565517 基本售价:
5830.0 元 规格:
50Tst
产品信息
概述货号 | 565517 |
描述 | The CW10 monoclonal antibody specifically binds to HVEM (Herpes virus entry mediator). HVEM is also known as CD270, Tumor necrosis factor receptor-like 2 (TR2), or LIGHT Receptor (LIGHT-R). CD270 is a type I transmembrane protein and member of the TNF Receptor superfamily. It is encoded by TNFRSF14 (tumor necrosis factor receptor superfamily member 14). CD270 is expressed on T cells, B cells, NK cells, monocytes, granulocytes, and some dendritic cells. CD270 binds to Lymphotoxin α (LTa3/TNFβ), CD258/LIGHT, CD272/BTLA, and glycoprotein D of Herpes simplex viruses HSV-1 and HSV-2. CD270-LIGHT interactions can reportedly transduce costimulatory signals for T cells whereas CD270-BTLA interactions can deliver inhibitory signals to T cells. |
别名 | TNFRSF14; HVEM; HVEA; LIGHTR ; ATAR ; TR2 |
同种亚型 | Mouse IgG1, κ |
反应种属 | Human (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Human Recombinant Protein |
标记 | BV421 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |