Hu OX40 Ligand BV421 ik-1 50Tst
货号：
563766 基本售价：
5830.0 元 规格：
50Tst
产品信息
概述| 货号 | 563766 |
| 描述 | The ik-1 monoclonal antibody specifically binds to OX40 Ligand (OX40L) which is also known as CD252 and CD134 Ligand. OX40L is encoded by TNFSF4 (Tumor necrosis factor (ligand) superfamily, member 4). OX40L a 34 kDa type II transmembrane glycoprotein that is expressed by dendritic cells, B cells, human umbilical vein endothelial cells (HUVEC) and other types of vascular endothelial cells. OX40L serves as a costimulatory ligand by binding to and signaling through OX40 (CD134) which is expressed on activated T cells. It also mediates adhesion of activated T cells or OX40-positive transformed cells to vascular endothelial cells. Monocyte-derived dendritic cells (MoDC) express OX40 Ligand after stimulation through CD40. Ligation of OX40 Ligand expressed by activated MoDC can significantly increase their cytokine production. |
| 别名 | CD252; OX40 Ligand; CD134 Ligand; CD134L; TNFSF4; GP34; TXGP1 |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human OX40 Ligand Transfected Cell Line |
| 标记 | BV421 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon BV421 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
