Hu HLA-ABC BUV395 G46-2.6 50Tst
货号:
565334 基本售价:
5700.0 元 规格:
50Tst
产品信息
概述货号 | 565334 |
描述 | The Human Leukocyte Antigen (HLA) complex is the human version of the MHC, helping the immune system distinguish the bodys own proteins versus those from foreign invaders, such as viruses. Humans have three main MHC class I genes, known as HLA-A, HLA-B and HLA-C. Major histocompatibility complex (MHC) class I molecules, which are widely found on the surface of nucleated cells, function by binding peptides and displaying them on the cell surface to cytotoxic T-cells. Intracellular degradation of cytosolic proteins by the proteasome generates many of the peptides that load MHC class I molecules. MHC class I may also serve as an inhibitory ligand for natural killer (NK) cell receptors (KIR, Killer Immunoglobulin-like Receptors), which viruses may modulate expression levels for to evade immune detection. The G46-2.6 monoclonal antibody binds to a monomorphic epitope on the alpha chain of HLA-A, HLA-B and HLA-C. |
别名 | Major histocompatibility complex, class I, A,B,C; HLA class I A,B,C |
同种亚型 | Mouse IgG1, κ |
反应种属 | Human (QC Testing) Rhesus, Cynomolgus, Baboon (Tested in Development) |
性能供应商 | BD Pharmingen |
标记 | BUV395 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BUV395 under optimum conditions, and unconjugated antibody and free BD Horizon™ BUV395 were removed.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |