Hu CD93 BUV737 R139 50ug
货号:
564934 基本售价:
5700.0 元 规格:
50ug
产品信息
概述货号 | 564934 |
描述 | The R139 monoclonal antibody specifically binds to CD93 which is also known as Complement component C1q receptor (C1qR), C1q receptor 1 (C1qR1), or Matrix-remodeling-associated protein 4 (MXRA4). The immunogen used to generate the R139 hybridoma was a preparation of CD93 protein. Human CD93 is a transmembrane glycoprotein that is highly expressed on monocytes, macrophages, granulocytes, and endothelial cells but not on T and B lymphocytes. CD93 is also known as the C1q/MBL/SPA Receptor as it binds C1q, the recognition subunit of the first component (C1) of the complement pathway, as well as MBL (Mannose-binding-lectin) and SPA (Pulmonary Surfactant Protein A). Human C1qRp is involved in the C1q-mediated enhancement of phagocytosis. R139 is suitable to detect CD93 expression on cells of myeloid lineage by flow cytometry, and CD93 in cellular lysates by Western blotting or immunoprecipitation. In addition, R139 reportedly neutralizes C1q-mediated enhancement of phagocytosis. CD93 has also been reported to define a human stem cell population with hematopoietic and hepatic potential. |
别名 | C1QR1; C1qRP; C1qR(P); C1q/MBL/SPA Receptor; MXRA4; GR11; Dj737e23.1 |
同种亚型 | Mouse BALB/c IgG2b, κ |
反应种属 | Human (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Clq-CLF-binding proteins |
标记 | BUV737 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BUV737 under optimum conditions, and unconjugated antibody and free BD Horizon BUV737 were removed.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |