Hu Cyclin B1 (aa 1-21) Pure GNS-1 250ug
货号:
554177 基本售价:
5662.0 元 规格:
250ug
产品信息
概述货号 | 554177 |
描述 | Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes. Cyclins (regulatory subunits) bind to cdks (catlytic subunits) to form complexes that regulate the progression of the cell cycle. The main cyclin-cdks complexes formed in vertebrate cells are cyclin D-cdk4 (G0/G1), cyclin E-cdk2 (G1/S), cyclin A-cdk2 (S) and cyclin B1-cdk1 (G2/M). These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small regulatory proteins, such as p21 and p27 [Kip1]. Cyclin B1 is a mitotic cyclin, where expression is normally low in G0/G1, increases in S and is maximal during the G2/M phase. Cyclin B1 is rapidly degraded at the end of mitosis, and is required for cells to exit from mitosis. This antibody has been reported to react to hamster and mouse cyclin B1. In addition, the GNS-1 antibody has been reported to recognize an epitope between amino acids 1-21 of human cyclin B1. |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) Mouse, Hamster (Reported) |
来源宿主 | Mouse |
使用方法 | FC, WB, IHC, IP, IF, Bioimg |
性能供应商 | BD Pharmingen |
免疫原 | Human Cyclin B1 Recombinant Protein |
存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |