HU GALECTIN-3 ALEXA 647 B2C10 50UG
货号：
565678 基本售价：
5330.0 元 规格：
50ug
产品信息
概述| 货号 | 565678 |
| 描述 | The B2C10 monoclonal antibody specifically recognizes Galectin-3 (GAL3/Gal-3) which is also known as, IgE-binding protein (εBP /IgEBP), Carbohydrate-binding protein 35 (CBP35), Galactoside-binding protein (GALBP), or MAC-2. Galectin-3 is a 30 kDa protein that is encoded by LGALS3 (lectin, galactoside-binding, soluble, 3) and belongs to the galactoside-binding lectins family. It is expressed by a variety of cell types including monocytes/macrophages, dendritic cells, some activated lymphocytes, fibroblasts, epithelial cells, and tumor cells. Galectin-3 has diverse functions and is involved in the induction and regulation of immune responses, inflammation, cell adhesion, chemotaxis, apoptosis, angiogenesis, and fibrosis. Galectin-3 can be differentially expressed in the nucleus, cytoplasm, and surface of cells and can be secreted. Galectin-3 levels can be markedly elevated in the nuclei of proliferating cells suggesting that it may play a role in cell growth regulation. Nuclear galectin-3 has been associated with gene expression and pre-mRNA splicing. Cell surface Galectin-3 reportedly serves as a non-integrin, laminin-binding protein, suggesting its role in cell adhesion to basement membranes. The B2C10 antibody is suitable for immunohistochemical staining of paraffin-embedded tissue sections. The B2C10 antibody reportedly crossreacts with mouse Galectin-3. |
| 别名 | LGALS3; Gal-3; GAL3; GALIG; GALBP; CBP35; MAC-2; IgE-binding protein; L31 |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Human (QC Testing) Mouse (Reported) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Recombinant Human Galectin-3 |
| 标记 | Alexa 647 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
