Hu Rag-1 Pure G189-1417 100ug
货号:
554116 基本售价:
5282.0 元 规格:
100ug
产品信息
概述货号 | 554116 |
描述 | Rag-1 and Rag-2 are recombination-activating genes expressed in maturing lymphoid cells. Both genes are required for variable-diversity-joining V(D)J DNA recombination at loci for immunoglobulin and T cell receptor genes. Ablation mutation of either Rag-1 or Rag-2 genes results in the lack of recombination in T and B cells. The normally lymphocyte-specific process of V(D)J recombination can be induced in fibroblasts by co-transfection of Rag-1 and Rag-2. Rag-1 and Rag-2 are both normally expressed in bone marrow and thymus, but only Rag-1 is expressed in the central nervous system. Rag-1 migrates at a reduced molecular weight of 105-120 kDa. Clone G189-1417 recognizes human Rag-1. It does not cross-react with Rag-2. It does not appear to recognize mouse Rag-1. Recombinant human Rag-1 was used as immunogen. |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | WB |
性能供应商 | BD Pharmingen |
免疫原 | Recombinant Human Rag-1 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |