Hu Angiostatin Pure C9-1 100ug
货号:
556902 基本售价:
5092.0 元 规格:
100ug
产品信息
概述货号 | 556902 |
描述 | The specific events which trigger the conversion of a primary malignant tumor into a more rapidly growing invasive neoplasm are largely unknown. One of the essential parameters for metastatic growth is the vascularization of the tumor, brought about by tumor angiogenesis factors. Recently, a new factor has been identified, designated angiostatin, which has been found to be an inhibitor of angiogenisis in a Lewis lung carcinoma animal model. Angiostatin is a 38 kDa proteolytic cleavage product of plasminogen, a 93 kDa protein. This factor has been shown to inhibit in vivo metastastic growth, regress primary tumors, as well as decrease the total number of vascular endothelial cells in vitro by inhibiting proliferation of these cells. The C9-1 clone recognizes the 93 kDa human plasminogen as well as the 38 kDa angiostatin fragment in western blot analysis. A recombinant protein containing the full length human angiostatin (361 amino acids, plus His Tag) was used as the immunogen. |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | WB, IP |
性能供应商 | BD Pharmingen |
免疫原 | Recombinant Human Angiostatin |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |