Hu Clk1 Pure G313-1 100ug
货号:
556388 基本售价:
5092.0 元 规格:
100ug
产品信息
概述货号 | 556388 |
描述 | Clk (also referred to as Sty) is a mammalian protein kinase that phosphorylates both serine/threonine and tyrosine residues. It belongs to the LAMMER family of dual specificity kinases that also includes KNS1 (from Saccharomyces cerevisiae), AFC (from Arabidopsis thaliana), and Doa (from Drosophila melanogaster). Family members share a highly conserved motif in a subdomain,EHLAMMERILGPLP, of the kinase domain. This motif is not conserved among kinases in general and may be involved in directing substrate specificity. LAMMER kinases are thought to play important roles in the control of cellular growth and differentiation. In particular, Clk has been shown to phosphorylate members of the serine/arginine-rich (SR) family of RNA splicing factors, suggesting that it may play a role in RNA processing. G313-1 recognizes Clk1. Full-length Clk1 migrates at a reduced molecular weight of ~57 kDa. A full-length Clk1-fusion protein was used as immunogen. |
同种亚型 | IgM |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | WB, IHC |
性能供应商 | BD Pharmingen |
免疫原 | Clk1-fusion protein |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |