Hu CD178 Pure NOK-2 100ug
货号：
556376 基本售价：
5092.0 元 规格：
100ug
产品信息
概述| 货号 | 556376 |
| 描述 | Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or Fas ligand (FasL). Fas belongs to the TNF (tumor necrosis factor)/NGF (nerve growth factor) receptor family, and is expressed in various tissue and cells including the thymus, liver, ovary, and lung. FasL is a 40kDa TNF family membrane protein that induces apoptosis by binding to Fas, its cell-surface receptor. FasL is expressed on activated T and NK cells. Both Fas and FasL are thought to play an important role in the apoptotic processes that take place during T cell development. NOK-2 recognizes human FasL. It recognizes both the membrane bound (FasL) and soluble (sFasL) forms. L5178Y mouse T lymphoma cells expressing recombinant human FasL were used as immunogen. FasL and sFasL migrate at reduced molecular weights of 40 and 26 kDa, respectively. However, the molecular weights observed in a particular sample may vary according to FasL and sFasL glycosylation and breakdown patterns as described in Tanaka et al. |
| 别名 | Fas Ligand, CD95 Ligand |
| 同种亚型 | IgG2a |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | ELISA, FA, IP |
性能| 供应商 | BD Pharmingen |
| 免疫原 | L51788Y Mouse T Lymphoma Cells Expressing Recombinant Human FasL |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
