Hu p21 Pure 6B6 100ug
货号:
554228 基本售价:
5092.0 元 规格:
100ug
产品信息
概述货号 | 554228 |
描述 | p21 belongs to a class of tumor suppressors including p16 and p27 which control progression through the cell cycle by inhibiting the activity of cyclin-cdk complexes. p21 is also known as senescent cell-derived inhibitor 1 (Sdi1), wild-type p53-activated fragment 1 (Waf1), Cdk-interacting protein 1 (Cip1), p21 and p53-regulated inhibitor of Cdks (Pic1). p21 mRNA is expressed at higher levels in senescent fibroblasts than in actively growing cells. When introduced into proliferating foreskin fibroblasts, p21 inhibits DNA synthesis and cell cycle arrest. p53 can activate p21 gene expression via a p53 binding site identified in the promoter of the p21 gene. |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | WB, IHC(Fr), IP, IHC(P) |
性能供应商 | BD Pharmingen |
免疫原 | Human p21 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |