Hu CD16 Pacific Blue 3G8 100ug
货号：
558122 基本售价：
4725.0 元 规格：
100ug
产品信息
概述| 货号 | 558122 |
| 描述 | The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes. The 3G8 antibody is reported (Vossebeld et al., 1997) to increase intracellular calcium levels in human neutrophils by interacting with bothFcγRIIa and FcγRIIIb molecules. This antibody has also been reported to induce homotypic neutrophil aggregation. |
| 别名 | FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3 |
| 同种亚型 | IgG1,κ |
| 反应种属 | Human (QC Testing) Cynomolgus, Rhesus, Baboon (Reported) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human polymorphonuclear leukocytes |
| 标记 | Pacific Blue |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody is conjugated to Pacific Blue™ under optimum conditions, and unreacted Pacific Blue™ was removed.
|
| 存储溶液 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
