Hu CD3 Alexa 647 MEM-57 25ug
货号：
566334 基本售价：
4700.0 元 规格：
25ug
产品信息
概述| 货号 | 566334 |
| 描述 | The human CD3 complex consists of four transmembrane proteins (γ, δ, ε, ζ) that are associated with the T cell antigen receptor (TCR) to form the CD3/TCR complex. The CD3 complex associates with either TCR αβ or TCR γδ heterodimers that are expressed by some thymocytes, T cells or NKT cells. The CD3 complex is required for the cell surface expression and signal-transducing functions of the TCR. The CD3 complex is expressed by ~60-85% thymocytes and ~60-80% of normal human peripheral blood lymphocytes. The MEM-57 monoclonal antibody reportedly recognizes the human CD3 epsilon subunit (CD3e/CD3ε, also known as T3E or TCRE) of the CD3/ TCR complex. CD3e is a ~20 kDa unglycosylated transmembrane protein that belongs to the Ig gene superfamily. CD3e has an Ig-like extracellular domain (ECD) and an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The MEM-57 antibody reportedly stimulates T cell proliferation and can induce cytotoxicity in some human T cell lines. |
| 别名 | CD3-epsilon; CD3E; T-cell surface antigen T3/Leu-4 epsilon chain; T3E; TCRE |
| 同种亚型 | Mouse IgG2a |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Thymocytes and T Lymphocytes |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
