Hu CD88 PE C85-4124 100Tst
货号：
552993 基本售价：
4675.0 元 规格：
100Tst
产品信息
概述| 货号 | 552993 |
| 描述 | The rabbit monoclonal antibody C85-4124 reacts with human CD88, which is also known as C5a anaphylatoxin Receptor (C5a receptor, C5aR). CD88 (C5aR) is a seven-transmembrane-spanning G-protein coupled receptor. Its ligand, C5a/C5a-desArg, is the 10 kDa cleavage product of serum protein C5, generated upon Complement System activation. Ligand binding activates the receptor, and mediates lysosomal enzyme release, cytokine and superoxide production, and chemotaxis. Ligand-occupied receptors get internalized (downregulated). Main cellular expression of CD88 (C5aR) includes granulocytes, monocytes, dendritic cells, astrocytes, and microglia. The extracellular, N-terminal 9-29 amino acids of the human C5aR sequence was used as an immunogen to generate C85-4124 monoclonal antibody from rabbits. |
| 别名 | C5a Receptor |
| 同种亚型 | IgG |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Rabbit |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human C5aR sequence aa. 9-29 |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
|
| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
