Hu MIG Pure B8-11 500ug
货号：
555038 基本售价：
4650.0 元 规格：
500ug
产品信息
概述| 货号 | 555038 |
| 描述 | The B8-11 monoclonal antibody specifically recognizes monokine induced by gamma interferon (MIG), which is also known as chemokine (C-X-C motif) ligand 9 (CXCL9). MIG is a chemotactic cytokine that belongs to the CXC subfamily of chemokines. MIG is predominantly expressed by monocytes, macrophages, hepatocytes, and endothelial cells in response to interferon-gamma (IFN- γ ) stimulation. It is primarily involved in the recruitment of activated T cells. MIG/CXCL9, and the closely-related IP10/CXCL10 and I-TAC/CXCL11 chemokines, exert their biological activities by binding to and signaling through the CXCR3 (CD183) chemokine receptor. CXCR3 is expressed on multiple cell types but predominantly on memory and effector T cells. The CXCL9 and CXCR3 interaction plays an important role in the onset of inflammation and is implicated in the pathogenesis of T-cell mediated immunity in several disease models. |
| 别名 | C-X-C motif chemokine 9; CMK; crg-10; Humig; SCYB9 |
| 同种亚型 | IgG1 |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC, ELISA Cap. |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Recombinant Human MIG Protein |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
