Hu DCIR Alexa 647 I3-612 100Tst
货号：
558220 基本售价：
4620.0 元 规格：
100Tst
产品信息
概述| 货号 | 558220 |
| 描述 | The I3-612 antibody reacts with DCIR, or dendritic cell immunoreceptor, a newly identified member of the calcium-dependent (C-type) lectin family. DCIR is a type II membrane glycoprotein with a single carbohydrate recognition domain (CRD). Its cytoplasmic tail contains a consensus immunoreceptor tyrosine-based inhibitory motif (ITIM). It is expressed on monocytes, macrophages, B-lymphocytes, granulocytes, but not on NK or T cells. DCIR is strongly expressed on dendritic cells derived from peripheral blood monocytes cultured in presence of GM-CSF and IL-4. Down-regulation is observed on these with further maturation using TNF- a or LPS. Reports describe the detection of two distinct inhibitory signals depending on its ITIM tyrosine residue. |
| 别名 | DCIR; CLECSF6; DCIR; HDCGC13P; LLIR |
| 同种亚型 | IgG1,κ |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human DCIR Recombinant Protein |
| 标记 | Alexa Fluor 647 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
