Hu IFN-Gma Horizon V450 B27 120Tst
货号：
560371 基本售价：
4560.0 元 规格：
120Tst
产品信息
概述| 货号 | 560371 |
| 描述 | The B27 monoclonal antibody specifically binds to human interferon- γ(IFN-γ).IFN-γ is a potent multifunctional cytokine that is produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ + T cells. IFN- γ exerts i ts biological effects through specific binding to the high-affinity IFN- γ Receptor Complex comprised of IFN- γRα (CD119) and IFN- γRβ subunits. In addition to its antiviral effects, IFN- γ upregulates a number of lymphoid cell functions including the antimicrobial and antitumor responses of macrophages, NK cells, and neutrophils. In addition, IFN- γ can exert strong regulatory influences on the proliferation, differentiation, and effector responses of B cell and T cell subsets. Th ese influences can involve IFN- γ ’s capacity to boost MHC class I and II expression by antigen-presenting cells as well as to direct effects on B cells and T cells t hemselves. Human IFN-γ is a 14- 18 kDa glycoprotein containing 143 amino acid residues. B27 is a neutralizing antibody. The use of B27 antibody for epitope mapping of human IFN- γ has been described. The B27 antibody has been reported not to bind to denatured IFN- γ. |
| 别名 | IFNG; Interferon-gamma; Interferon-γ; Type II interferon; MAF |
| 同种亚型 | IgG1,κ |
| 反应种属 | Human (QC Testing) Rhesus, Cynomolgus, Baboon (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | IC/FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human IFN-γ Recombinant Protein |
| 标记 | V45 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ V450 under optimum conditions, and unreacted BD Horizon™ V450 was removed.
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| 存储溶液 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
