Hu Hobit Alexa 647 Sanquin-Hobit/1 50Tst
货号：
566250 基本售价：
4465.0 元 规格：
50Tst
产品信息
概述| 货号 | 566250 |
| 描述 | The Sanquin-Hobit/1 monoclonal antibody specifically binds to Homolog of Blimp-1 in T cells (Hobit), which is also known as Zinc finger protein 683 (ZNF683). Hobit is a conserved Zn-finger transcription factor that is homologous to Blimp-1. It is expressed in cytotoxic effector-type CD8+ T cells and in some effector memory CD8+ T cells, but is not significantly expressed in naοve or most central memory CD8+ T cells. Hobit is also expressed in natural killer (NK) cells, and NKT cells, but is not expressed in CD4+ T cells, B cells, monocytes, dendritic cells, or neutrophils. Hobit expression is strongly correlated with the expression T-bet and Interferon- γ(IFN-γ ) mRNA. Hobit appears to play a role in the differentiation and effector functions of NK cells and effector CD8+ T cells such as in the production of IFN- γ. |
| 别名 | HOBIT; Homolog of Blimp-1 in T cells; Zinc finger protein 683; ZNF683 |
| 同种亚型 | Mouse BALB/c IgM, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Hobit Recombinant Protein |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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| 存储溶液 | Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. |
