Hu CD172B BB515 B4B6 25Tst
货号：
566019 基本售价：
4250.0 元 规格：
25Tst
产品信息
概述| 货号 | 566019 |
| 描述 | The B4B6 monoclonal antibody specifically binds to CD172b, which is also known as S ignal regulatory protein β (SIRPβ) , or SIRP-beta-1 (SIRPB1/SIRP β 1). CD172b is a 50 kDa, type I transmembrane glycoprotein that belongs to the SIRP family within the Ig gene superfamily. CD172b has a transmembrane domain that contains a positively-charged lysine residue. This allows CD172b to interact with a transmembrane signaling adaptor protein, DAP12/KARAP, and transduce stimulatory signals into cells. CD172b is expressed on monocytes, macrophages, dendritic cells, and granulocytes. It is not expressed on CD34+ cells. CD172b/SIRPβ and its counterpart, CD172a/SIRP α , appear to have complementary roles in signal regulation and may work together in tuning cellular responses to certain ligands. |
| 别名 | SIRPB1; SIRP-BETA-1; SIRPβ1; SIRPbeta; SIRP beta |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human SIRPβ1 extracellular domain Recombinant Protein |
| 标记 | BB515 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BB515 under optimum conditions and unconjugated antibody was removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
