Hu CD41A APC-H7 HIP8 50Tst
货号:
561422 基本售价:
4140.0 元 规格:
50Tst
产品信息
概述货号 | 561422 |
描述 | The HIP8 monoclonal antibody specifically binds to the α-chain of CD41. CD41 is also known as Integrin αIIb or Platelet GPIIb. The calcium-dependent complex of CD41 and CD61 (β3 integrin or GPIIIa) is normally expressed on platelets and megakaryocytes. The CD41/CD61 complex is the receptor for fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. CD41 (clone HIP8) completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. This antibody is useful in the morphological and physiological studies of platelets and megakaryocytes. |
别名 | ITGA2B; Integrin alpha-2b (αIIb); Platelet glycoprotein IIb (GPIIb) |
同种亚型 | IgG1,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC |
性能供应商 | BD Pharmingen |
免疫原 | Purified platelet membrane glycoproteins |
标记 | APC-H7 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with APC-H7 under optimum conditions, and unconjugated antibody and APC-H7 were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
|
存储溶液 | Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. |