Hu CD294 Alexa 647 BM16 100ug
货号:
558042 基本售价:
3900.0 元 规格:
100ug
产品信息
概述货号 | 558042 |
描述 | The BM16 monoclonal antibody specifically binds to CD294. CD294 is encoded by PTGDR2(Prostaglandin D2 receptor 2) and is also known as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), GPR44 (G protein-coupled receptor 44), DL1R, and DP2. CD294 is a member of the G protein-coupled leukocyte chemoattractant receptor family and it is expressed on Th2, but not Th1 type cells. CD294 is detectable on CD4+ T cells in fresh PBMC but not on B cells and NK cells. CD294 is also expressed on peripheral blood basophils and eosinophils, suggesting its involvement allergic reactions. Phenotypic analysis of CD4+ T cells expressing CRTH2 demonstrated that they were also CD45RA-negative and CD45RO+ and CD25+. These cells produce Th2- but little or no Th1-type cytokines upon stimulation with PMA and Ionomycin. |
别名 | CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44 |
同种亚型 | IgG2a,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Rat |
使用方法 | FC |
性能供应商 | BD Pharmingen |
免疫原 | Human CRTH2 Transfected Cell Line |
标记 | Alexa Fluor 647 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |