Hu CD80 Biotin BB1 100Tst
货号：
555682 基本售价：
3800.0 元 规格：
100Tst
产品信息
概述| 货号 | 555682 |
| 描述 | Reacts with a 60 kD transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human Differentiation Antigens. There have been several recent studies reporting discrepancies in the expression and function of CD80 when the BB1 clone is used compared to other anti-CD80 monoclonals (e.g., L307.4). Caution should therefore be used in the interpretation of data generated using BB1, as reports indicate that BB1 may recognize, in addition to CD80, CD74 and even possibly another as yet undefined molecule. CD80, amember of the Ig supergene family, is expressed on activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells: CD28 and CD152 (CTLA-4). CD80 is also expressed in activated CD4+ and CD8+ T cells, appearing late after activation, suggesting that activated T cells may be capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 molecule by CD28 mAb or by CD80 antigen results in T-cell activation and a signal for IL-2 production. |
| 别名 | B7-1 |
| 同种亚型 | IgM,κ |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 标记 | Biotin |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
