Hu CD49d BV480 9F10 25Tst
货号：
566183 基本售价：
3700.0 元 规格：
25TST
产品信息
概述| 货号 | 566183 |
| 描述 | The 9F10 monoclonal antibody specifically reacts with the integrin α 4 chain, that is expressed as a heterodimer with either of two β integrin subunits, β 1 (CD29) or β 7. The α4β 1 integrin (VLA-4) is expressed on lymphocytes, monocytes, thymocytes, NK cells, and several B- and T-cell lines, and mediates binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. The α4β 7 integrin has a similar tissue distribution, except it is found on only a small subpopulation of thymocytes. Integrin α4β 7 also binds fibronectin and VCAM-1, and has been shown in the mouse to preferentially bind the mucosal vascular addressin molecule, MAdCAM-1. This antibody is useful for studies of the expression by and function of cells that express α 4 chain-containing integrins. This clone cross-reacts with a subset of peripheral blood lymphocytes, monocytes, and some granulocytes of baboon and both rhesus and cynomolgus macaque monkeys. The distribution on leukocytes is similar to that observed with human peripheral blood leukocytes. |
| 别名 | Integrin α4 chain; Integrin alpha 4; ITGA4; IA4; alpha 4 subunit of VLA-4 |
| 同种亚型 | Mouse IgG1, κ |
| 反应种属 | Human (QC Testing) Cynomolgus, Dog, Cow, Cat, Sheep, Horse, Rhesus, Baboon (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV480 under optimum conditions, and unconjugated antibody and free BD Horizon BV480 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
