Hu CD117 BV421 YB5.B8 100Tst
货号:
562434 基本售价:
3700.0 元 规格:
100Tst
产品信息
概述货号 | 562434 |
描述 | The YB5.B8 monoclonal antibody specifically binds to CD117. CD117, also known as c-Kit, is a 145 kDa cell-surface glycoprotein with tyrosine kinase activity. CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes. CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF). The interaction of c-Kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development. The ability of the YB5.B8 antibody to block the binding of c-Kit ligand is still controversial. |
别名 | KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor |
同种亚型 | Mouse IgG1, κ |
反应种属 | Human (QC Testing) |
性能供应商 | BD Pharmingen |
免疫原 | Acute myelocytic leukemia blasts |
标记 | BV421 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |