Hu Invar NK T-Cell BV711 6B11 50Tst
货号：
563268 基本售价：
3575.0 元 规格：
50Tst
产品信息
概述| 货号 | 563268 |
| 描述 | Monoclonal antibody 6B11 reacts with a unique determinant in the CDR3 region of the invariant (V α24-Jα Q) TCR chain. Thus 6B11 identifies a subset of all V α 24 positive T cells. The binding of the PE-conjugate of 6B11 can be partially blocked by other antibodies specific for V α 24 (BD Biosciences Pharmingen, data not shown). This invariant chain is expressed on invariant NK T cells, which are a small subset of T lymphocytes that also express other NK cell molecules such as CD161. Invariant NK T cells have been reported to play an immunoregulatory role. The V α24-Jα Q interacts with the CD1d protein. Invariant NK T cells can be specifically activated by CD1d-presented antigen resulting in rapid production of IL-4 and IFN (also known as IFN- γ ). Studies of NK T cells describe their role in anti-tumor immunity and autoimmunity. |
| 别名 | Vα24JαQ TCR Chain |
| 同种亚型 | Mouse C57BL/6 IgG1, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Peptide from CDR3 loop of the invariant TCR V24 sequence |
| 标记 | BV711 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV711 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV711 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
