Hu IFN-Gma FITC B27 100ug
货号：
554700 基本售价：
3520.0 元 规格：
100ug
产品信息
概述| 货号 | 554700 |
| 描述 | The B27 monoclonal antibody specifically binds to human interferon- γ(IFN-γ).IFN-γ is a potent multifunctional cytokine that is produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ + T cells. IFN- γ exerts i ts biological effects through specific binding to the high-affinity IFN- γ Receptor Complex comprised of IFN- γRα (CD119) and IFN- γRβ subunits. In addition to its antiviral effects, IFN- γ upregulates a number of lymphoid cell functions including the antimicrobial and antitumor responses of macrophages, NK cells, and neutrophils. In addition, IFN- γ can exert strong regulatory influences on the proliferation, differentiation, and effector responses of B cell and T cell subsets. Th ese influences can involve IFN- γ ’s capacity to boost MHC class I and II expression by antigen-presenting cells as well as to direct effects on B cells and T cells t hemselves. Human IFN-γ is a 14- 18 kDa glycoprotein containing 143 amino acid residues. B27 is a neutralizing antibody. The use of B27 antibody for epitope mapping of human IFN- γ has been described. The B27 antibody has been reported not to bind to denatured IFN- γ. |
| 别名 | IFNG; Interferon-gamma; Interferon-γ; Type II interferon; MAF |
| 同种亚型 | IgG1,κ |
| 反应种属 | Human (QC Testing) Rhesus, Baboon, Cynomolgus (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | IC/FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human IFN-γ Recombinant Protein |
| 标记 | FITC |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
