Hu CDw93 Pure R3 100ug
货号:
551454 基本售价:
3520.0 元 规格:
100ug
产品信息
概述货号 | 551454 |
描述 | The immunogen used to raise R3 was C1q-binding protein preparation as described. Human C1qRp is a 631 a.a. protein (~66.5 kD) protein that is highly expressed on monocytes/macrophages, neutrophil granulocytes but not on T and B lymphocytes. C1qRp binds C1q, the recognition subunit of the first component (C1) of the complement pathway, as well as MBL (Mannose-binding-lectin) and SPA (Pulmonary Surfactant Protein A). Human C1qRp is involved in the C1q-mediated enhancement of phagocytosis. R3 is suitable to detect C1qRp expression on cells of myeloid lineage by flow cytometry, C1qRp in cellular lysates by Western blotting or immunoprecipitation. Pretreatment of monocytes with R3 neutralizes C1q-mediated enhancement of phagocytosis. In addition, when immobilized, R3 mimics C1q- MBL- or SPA-mediated enhancement of phagocytosis as reported. CDw93 (C1qRp) has been reported to define a human stem cell population with hematopoietic and hepatic potential. |
别名 | C1qRp |
同种亚型 | IgM,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC, WB, IP |
性能供应商 | BD Pharmingen |
免疫原 | C1q-binding protein |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |