Hu TRA-1-60 AG BUV395 TRA-1-60 25Tst
货号:
566205 基本售价:
3280.0 元 规格:
25TST
产品信息
概述货号 | 566205 |
描述 | The TRA-1-60 monoclonal antibody reacts with the neuraminidase-resistant form of a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-60 antigen is a sialylated epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-81, GCTM2, K4, and K21. The expression of TRA-1-60 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. TRA-1-60 antigen is released into the serum of patients bearingtesticular tumors containing EC cells. As human EC and ES cells undergo differentiation, expression of TRA-1-60 antigen is lost. Expression of TRA-1-60 antigen has also been observed on a rhesus monkey ES cell line (Thomson et al, 1995). |
别名 | TRA-1-60(R) |
同种亚型 | Mouse BALB/c IgM, κ |
反应种属 | Human (QC Testing) Rhesus, Monkey (Reported) |
性能供应商 | BD Pharmingen |
免疫原 | Human Embryonal Carcinoma Cell Line |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BUV395 under optimum conditions, and unconjugated antibody and free BD Horizon™ BUV395 were removed.
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存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |