Hu CLA IHC Pure HECA-452 1mL
货号：
550407 基本售价：
3240.0 元 规格：
1mL
产品信息
概述| 货号 | 550407 |
| 描述 | The HECA-452 monoclonal antibody specifically reacts with Cutaneous Lymphocyte Associated Antigen (CLA), a carbohydrate domain shared by sialyl Lewis[x] (sLe[x]) and sialyl Lewis[a] (sLe[a]) antigens. It serves as a ligand for selectins including CD62E (E-selectin; ELAM-1). CLA is expressed on high endothelium and on lymphocytes including most T lymphocytes infiltrating cutaneous sites of inflammation. Amongst peripheral blood cells, it is expressed on monocytes and granulocytes and a subset of lymphocytes. The HECA-452 antibody is also reportedly crossreactive with the mouse CLA carbohydrate epitope that is transiently expressed by PSGL-1/CD162 on activated T cells. A number of studies suggest that CLA plays an important role in supporting leucocyte adhesive interactions and migration into extravascular tissues during inflammation. |
| 别名 | CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG |
| 同种亚型 | IgM,κ |
| 反应种属 | Human (QC Testing) Mouse (Reported) |
| 来源宿主 | Rat |
| 使用方法 | IHC(Fr), IHC(F)* |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Lymphocyte-depleted Stromal Preparation of Tonsil |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
