Hu CD64 BUV737 10.1 100Tst
货号：
564425 基本售价：
3160.0 元 规格：
100Tst
产品信息
概述| 货号 | 564425 |
| 描述 | The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation. |
| 别名 | FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1 |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Human (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes |
| 标记 | BUV737 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BUV737 under optimum conditions, and unconjugated antibody and free BD Horizon BUV737 were removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
